Classification and etiologies of gestational trophoblastic disease
نویسندگان
چکیده
Various forms of trophoblastic diseases were reported in the literature, including complete and partial hydatidiform moles, gestational choriocarcinomas, placental-site epitheloid tumors. Among patients who suffer from mole, neoplasia can be easily diagnosed by using levels human chorionic gonadotropin (hCG). Therefore, complex investigations are not usually necessary measuring hCG, physical examination assessments. In addition, patients’ medical history help attending physicians to draw an adequate treatment plan for with neoplasia. However, Pelvic Doppler ultrasonography might also used additional assessments, presence or absence pregnancy, measurement uterine volume size. Additionally, it determines vasculature spread neoplasm within pelvic region. Furthermore, genetic analysis differentiate between types disease. Moreover, among staging classification systems, international federation gynecology obstetrics (FIGO) seems best efficacious modality determination prognosis various disease properly choose modality.
منابع مشابه
Gestational trophoblastic disease II: classification and management of gestational trophoblastic neoplasia.
Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. The overall cure rate in treating these tumors is currently >90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity. Nonmetastatic (stage I) and low-risk metastat...
متن کاملGestational Trophoblastic Disease
In partial molar pregnancies, the trophoblast cells have three sets of chromosomes (triploid). Two sperm are believed to fertilise the ovum at the same time, leading to one set of maternal and two sets of paternal chromosomes. Around 10% of partial moles are tetraploid or mosaic in nature. There is usually evidence of fetal tissue or fetal blood cells in a partial molar pregnancy. An embryo may...
متن کاملGestational trophoblastic disease.
BACKGROUND Molar pregnancy represents a significant burden of disease on the spectrum of Gestational Trophoblastic Disease (GTD). The incidence appears to be quite high in South Asia. The objective of this study was to determine the frequency of GTD, and clinical presentation, management and outcome of patients with molar pregnancy. METHODS This retrospective, descriptive study was conducted ...
متن کاملGestational trophoblastic disease.
OBJECTIVE To provide standards for the diagnosis and treatment of patients with hydatidiform mole and gestational trophoblastic tumours (GTT). OPTIONS Prognostic factors useful for treatment decisions in GTT are defined with patients classified as low-, medium-, and high-risk groups. OUTCOMES Improved mortality and morbidity. EVIDENCE Evidence was gathered using Medline for relevant studi...
متن کاملGestational trophoblastic disease.
Patients diagnosed with molar pregnancy are treated by either suction curettage or hysterectomy, depending on their desire to preserve fertility. We use single-agent chemotherapy, preferably methotrexate, to treat low- or moderate-risk persistent trophoblastic tumors. High-risk patients who have metastatic disease are treated primarily with combination chemotherapy and, as indicated, adjuvant r...
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ژورنال
عنوان ژورنال: International Journal of Community Medicine and Public Health
سال: 2021
ISSN: ['2394-6032', '2394-6040']
DOI: https://doi.org/10.18203/2394-6040.ijcmph20213217